Top 10 Pharmaceutical Contract Manufacturing Companies in the USA
In the fast-evolving pharmaceutical industry, Contract Manufacturing Organizations (CMOs) play a vital role by offering specialized production capabilities, regulatory expertise, and cost-effective solutions. Pharmaceutical companies often partner with CMOs to manufacture drugs, supplements, and medical products without the need for heavy capital investment. Here’s a look at the top 10 pharmaceutical contract manufacturing companies in the USA, known for their innovation, reliability, and compliance with FDA standards.
1. Avara Pharmaceutical Services
Avara Pharmaceutical Services is a leading contract development and manufacturing organization (CDMO ) specializing in oral solid dose and sterile injectable products. With global facilities and a strong focus on quality, compliance, and customer satisfaction, Avara delivers reliable, flexible solutions to pharmaceutical clients seeking excellence in manufacturing and supply chain support.
2. EZ-Life Pharmaceuticals
Ez-Life Pharmaceuticals is a trusted name in the pharmaceutical industry, known for its innovation, quality, and versatility in product development. With a strong foundation in research and manufacturing, Ez-Life excels in creating a wide range of pharmaceutical formulations, including topicals, liquids, semi-solids, gels, ointments, suppositories, and more.
What sets Ez-Life apart is its ability to adapt to the evolving needs of healthcare brands. Whether it’s a custom formulation or a private-label solution, the company delivers GMP-compliant, cost-effective, and scalable services with a commitment to safety and regulatory excellence.
From early-stage development to final packaging, Ez-Life Pharmaceuticals provides end-to-end support backed by technical expertise and advanced facilities. Its diverse capabilities make it an ideal partner for OTC medications, supplements, personal care products, and medical device packaging.
3. AbbVie Contract Manufacturing
AbbVie CMO leverages decades of expertise in complex formulation and biologics. They offer services in small molecules, biologics, and custom APIs, with a strong reputation for quality and innovation.
4. AGC Biologics
AGC Biologics is a leading global contract development and manufacturing organization (CDMO) specializing in biologics. With state-of-the-art facilities and end-to-end services, AGC Biologics supports clinical to commercial production of therapeutic proteins, antibodies, and advanced therapies, ensuring high quality, innovation, and regulatory compliance for pharmaceutical and biotech partners worldwide.
5. Recro Pharma (now Societal CDMO)
Specializing in oral solid dosage forms, Recro Pharma—rebranded as Societal CDMO—is known for its expertise in modified-release technologies and DEA Schedule I-V controlled substances.
6. Catalent Pharma Solutions
Headquartered in Somerset, New Jersey, Catalent is one of the most recognized names in the global contract manufacturing space. With advanced technologies in biologics, oral dosage forms, and gene therapies, Catalent supports everything from early-stage development to commercial-scale production.
7. Lonza
Though headquartered in Switzerland, Lonza operates significant U.S. manufacturing facilities. Their services include biologics, cell and gene therapies, and highly potent APIs. Lonza is trusted by startups and global pharma leaders alike for its regulatory strength and scientific capabilities.
8. Cambrex Corporation
With several U.S.-based cGMP facilities, Cambrex specializes in small molecule drug substance and drug product manufacturing. They offer development services from preclinical to commercial stages.
9. DPT Laboratories
A leading provider of semi-solid and liquid dosage form manufacturing, DPT Laboratories (a MANA company) offers end-to-end services from formulation to final product packaging. Their expertise is especially strong in topical and sterile products.
10. PCI Pharma Services
PCI provides integrated solutions across the pharmaceutical supply chain, including clinical trial services, commercial packaging, and manufacturing. Known for their global capabilities and U.S. presence, PCI works with both emerging biotech firms and large pharmaceutical corporations.
The pharmaceutical contract manufacturing industry in the U.S. is highly competitive, with companies focusing on quality, regulatory compliance, and technological innovation. Whether you’re a startup looking to scale production or a large pharma company seeking flexible manufacturing solutions, the above-listed CMOs represent the best in the business.
Choosing the right partner can significantly accelerate time-to-market, reduce costs, and ensure product quality — making it crucial to work with a trusted, experienced CMO.